The anti-Creation side asserts that the following assumptions are necessary for science, even claiming that not accepting these assumptions makes science or engineering impossible to do:

• the assumption that assumptions are necessary for scientific conclusions (the conclusions can be based on assumptions).
• the assumption that we can use assumptions to establish knowledge
• the assumption that there’s no difference between knowledge established by direct observation and knowledge established by arbitrary assumptions,made-up stories, plus direct observation so long as a majority of scientists accept the assumptions and stories
• the assumption that anyone who won’t accept the anti-Bible assumptions can’t do science or engineering
• the assumption that anti-Bible assumptions aren’t arbitrary like all other assumptions but are based on “experience”
• the assumption that there’s no Creator God enforcing all the natural laws, but rather random chance–Naturalism, and the laws of nature just happen to be the way they are for no particular reason
• the assumption that God didn’t create but everything just happened
• the assumption that the big bang happened even though we don’t know how nothing could have caused everything
• the assumption that God sent no worldwide, catastrophic Flood (the arbitrary assumption of Uniformitarianism as opposed to Catastrophism)
• the assumption that the big-bang-billions-of-years-molecules-to-man story is science and to question it is unscientific
• the assumption that all the thousands of other arbitrary assumptions and stories that are needed in order to keep big-bang-billions-of-years-molecules-to-man alive are valid and to be accepted as true without any evidence
• the assumption that science will eventually find ways to explain how matter could have created itself, how information could be added to cells, how the first self-replicating life could have formed, where the laws of nature came from, and all the other unanswered questions (mysteries) that seem to indicate that the big-bang-billions-of-years-molecules-to-man story is just a lie

The Creation side asserts that the following revelation (which God speaks through the Bible and through personal experience with Jesus Christ) is the necessary for science, since not accepting this revelation results in science based on arbitrary assumptions:

• the revelation that assumptions are arbitrary and not a valid basis for conclusions
• the revelation that when we go beyond what can be observed or what God has revealed through Scripture, we ought not to be dogmatic
• the revelation that God is the source of all the laws of science and the reason that we can know that those laws will be faithfully upheld
• the revelation that God created the Heavens and the Earth and everything in them in six days
• the revelation that mankind fell into sin, and having been given dominion over the Earth, brought Creation into the Fall
• the revelation that the curse of death and sorrow is the natural consequence that followed from the Fall into sin
• the revelation that God sent the worldwide, catastrophic Genesis Flood as the consequence of sin
• the revelation that God caused the confusion of languages because of the rebellion of mankind
• the revelation that mankind was, and is, not able to fulfill righteousness by obeying rules
• that God came to Earth in the form of Jesus to save us by paying the price of sin and God’s plan to remove sin from anyone who will come to Him
• the revelation that God will ultimately judge of every person according to His wisdom and holiness
• the revelation that part of science is logic. If logic is used in a way that creates the illusion of being able to know something when the thing claimed isn’t really known, then logic is useless. It’s a fallacy. It’s a lie.